Characterization of Oil-in-water Gelatin Emulsion Gels: Effect of Homogenization Time

Thakur, Goutam and Mitra, Analava and Basak, Amit and Rousseau, Derick and Pal, Kunal (2010) Characterization of Oil-in-water Gelatin Emulsion Gels: Effect of Homogenization Time. In: Proceedings of 2010 International Conference on Systems in Medicine and Biology, 16-18 December 2010, liT Kharagpur, India.

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Abstract

Oil-in-water emulsion gels consisting sunflower oil as the internal phase and a chemically-crosslinked gelatin solution as the continuous aqueous phase were developed. The dispersion was homogenized at 60°C in a high pressure valve homogenizer at a pressure of 5000/500psi for different time periods (2, 5 or 10 min). The homogenized samples were formed into films at 5°C followed by crosslin king with genipin at room temperature. The microstructure of the gels was studied using confocal laser scanning microscopy. The results showed significant differences in the microstructure depending on homogenization time. Gel micrographs indicated a well-dispersed network of sunflower oil droplets in the gelatin matrix with a higher homogenization duration (10 min) while a less unorganized gel microstructure was evident at shorter homogenization times (2 and 5 min). Gels were also characterized using colourimetric analysis. Puncture tests of the gels were tested to establish their mechanical stability. The gels prepared with 10 min homogenization exhibited the highest puncture strength (0.23±0.20 MPa) (p<0.05). These results demonstrated that gelatin gels homogenized for longer periods were more stable, thus expanding their range of possible biomedical applications.

Item Type: Conference or Workshop Item (Paper)
Uncontrolled Keywords: gelatin; emulsion gel; homogenization; genipin; crosslin king; microstructure
Subjects: Engineering > MIT Manipal > Biomedical
Depositing User: MIT Library
Date Deposited: 29 Jul 2011 09:55
Last Modified: 29 Jul 2011 09:55
URI: http://eprints.manipal.edu/id/eprint/1092

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