Genipin Crosslinked N Methylene Phosphonic Chitosan Bio-hydrogels

Datta, Pallab and Thakur, Goutam and Chatterjee, Jyotirmoy and Dhara, Santanu (2011) Genipin Crosslinked N Methylene Phosphonic Chitosan Bio-hydrogels. In: 3rd International Congress on Biohydrogels, November 8-12, 2011, Florence , Italy. (Submitted)

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Studies have shown improved cellular adhesion, calcium phosphate mineralization, and gene delivery achieved by phosphorylated derivative of chitosan. In paraller, role of phosphoproteins, phospholipids, proteoglycans and phosphoglycans in regulating many of these cellular responses is increasingly bing elucidated. Thus biocompatible hydrogel of phosponic chitosan (PC) may prove to be an useful analogue of the phosphomacromolecules. This work is a first time report on the gelation of PC by genipin (G) a non-toxic crosslinker.

Item Type: Conference or Workshop Item (Paper)
Subjects: Engineering > MIT Manipal > Biomedical
Depositing User: MIT Library
Date Deposited: 01 Aug 2011 11:26
Last Modified: 01 Aug 2011 11:26

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