A Study of The Effect of Antioxidant Status on the Outcome of Malignant Gliomas

Rao, Anjali and Rao, Gayathri M and Prabhu, Krishnananda and Reddy, Gummadi Maheshwar and Rao, Suryanarayana and Raja, Annaswamy (2010) A Study of The Effect of Antioxidant Status on the Outcome of Malignant Gliomas. Journal of Hainan Medical College, 16 (1). pp. 38-46.

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Objective:To explore the relationship of the effect of antioxidant status of patients with malignant gliomas at the time of their admission to a tertiary care hospital and the clinical condition after a post operative follow up over a period of two years. Methods:Several antioxidant enzymes like erythrocytic glutathione reductase, glutathione peroxidase,catalase,superoxide dismutase,plasma ceruloplasmin,antioxidant vitaminsA,E and C and lipid peroxidation products like erythrocytic thiobarbituric acid reacting substances and plasma conjugated diene swere analyzed both in controls and glioma patients. Results: It was observed that patients who exhibited an overall higher turn over of an-tioxidants presented with recurrence. Conclusion: Free radical toxicity may adversely affect the out come of such cancer patients.

Item Type: Article
Uncontrolled Keywords: Malignantgliomas,Historical cohor,Antioxidant status,Outcome
Subjects: Medicine > KMC Manipal > Biochemistry
Medicine > KMC Manipal > Neurology
Depositing User: KMC Manipal
Date Deposited: 25 Aug 2011 04:27
Last Modified: 16 Nov 2011 09:55
URI: http://eprints.manipal.edu/id/eprint/1185

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