An era of adjuvant therapies for oral pemphigus

Shenoy , N and Ongole , R and *, Sumanth KN and Shenoy , AK (2009) An era of adjuvant therapies for oral pemphigus. Journal of Nepal Dental Association, 10 (1). pp. 75-78.

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Abstract

Pemphigus vulgaris (PV) is an autoimmune disease characterized by blistering and erosions on skin and mucous membranes due to acantholysis. It is the second most common chronic bullous dermatosis; next to bullous pemphigoid. The use of corticosteroids since the 1950s has reduced the mortality from 60% - 90% to about 30%, but it still carries signifi cant morbidity. The mainstay of treatment even today remains to be corticosteroids with or without other adjuvant therapies such as immunosuppressive agents, anti-infl ammatory agents and immunomodulatory drugs. This paper emphasizes on popular adjuvant therapies that can help achieve long term remission even in case of recalcitrant lesions of pemphigus vulgaris.

Item Type: Article
Uncontrolled Keywords: Corticosteroid therapy, Pemphigus vulgaris
Subjects: Dentistry > MCODS Mangalore > Oral Medicine and Radiology
Medicine > KMC Mangalore > Pharmacology
Depositing User: KMCMLR User
Date Deposited: 30 Aug 2011 10:13
Last Modified: 17 Oct 2011 07:17
URI: http://eprints.manipal.edu/id/eprint/1242

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