Isolated Gonadotropin deficiency associated with empty sella.

Chowta, Mukta N and Chowta, Nithyananda K (2008) Isolated Gonadotropin deficiency associated with empty sella. Annals of Tropical Medicine & public Health, 1 (2). pp. 68-69. ISSN 1755-6783

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Empty sella syndrome may be associated with abnormal pituitary function. Low levels of growth hormone (GH)are most common, but other pituitary hormones may also be deficient. Case Report: The patient was a 30-year-old male who presented with complaints of failure to attain puberty, break in voice, gynecomastia, marfanoid features, under developed genitalia, and testicular atrophy. He had eunuchoid body proportions with a height of 177 cm, an arm span of 183 cm, a lower segment of 101 cm, and a sitting height of 79 cm. There was no anosmia or midline defects.A computed tomography scan showed empty sellaturcica. Magnetic resonance imaging of the brain showed a hypoplastic pituitary within empty sellaturcica and cerebrospinal fluid (CSF) collection surrounding the gland. Hislaboratory investigations showed low luteinizing hormone (LH), follicle stimulating hormone (FSH), and testosterone levels. The patient was treated with testosterone replacement and human chorionic gonadotropin (HCG). His condition improved after therapy except for persisting azoospermia. Conclusion: Uncommon presentation of isolated gonadotropin deficiency leading to delayed puberty due to pituitary cause.

Item Type: Article
Uncontrolled Keywords: Empty sella, gonadotropin, hypogonadism
Subjects: Medicine > KMC Mangalore > Pharmacology
Medicine > KMC Mangalore > Medicine
Depositing User: KMCMLR User
Date Deposited: 19 Sep 2011 06:08
Last Modified: 18 Oct 2011 06:23

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