Sublingual misoprostol: a better choice for cervical priming before manual vacuum aspiration

Shetty, Jyothi and Chawla, R and Pandey, D and Kamath, A and Guddattu, Vasudeva (2010) Sublingual misoprostol: a better choice for cervical priming before manual vacuum aspiration. Indian Journal of Medical Sciences, 64 (8). pp. 356-362.

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Abstract

BACKGROUND:Misoprostol is effective for cervical priming before manual vacuum aspiration (MVA). Aim of study was to determine whether sublingual misoprostol with a shorter interval of 2 hours before MVA would be as effective as its standard vaginal administration. STUDY DESIGN: This randomized control trial included 82 women randomly assigned to receive 400 mcg of misoprostol, either sublingually or vaginally. MVA was performed 2 hours and 3 hours after in sublingual and vaginal group, respectively. RESULTS: Cervical dilatation of 8 mm was achieved within 2 hours in sublingual group. Mean time taken for procedure (14.4 ± 5.3: sublingual group and 16.2 ± 5.7: vaginal group), and blood loss was comparable (12.2 ± 9.7 ml in sublingual group and 13.7 ± 8.5 ml in vaginal group). CONCLUSION: 2 hour of cervical priming with 400 mcg of sublingual misoprostol before MVA was as good as 3 hours with vaginal administration of the same dose.

Item Type: Article
Uncontrolled Keywords: Cervical priming, manual vacuum aspiration, misoprostol, sublingual group, vaginal group
Subjects: Departments at MU > Statistics
Medicine > KMC Manipal > Obstetrics & Gynaecology
Depositing User: KMC Manipal
Date Deposited: 31 May 2013 04:31
Last Modified: 31 May 2013 04:31
URI: http://eprints.manipal.edu/id/eprint/136185

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