Analysis of hemogram profile of elderly diabetics in a tertiary care hospital

Chowta, Mukta N. and Chowta, Nithyananda K. and Adhikari, Prabha and Shenoy, Ashok K. (2013) Analysis of hemogram profile of elderly diabetics in a tertiary care hospital. International Journal of Nutrition, Pharmacology, Neurological Diseases, 3 (2). pp. 126-130. ISSN 2231-0738

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Abstract

Background: Anemia is a common concern in geriatric health, but its exact incidence and prevalence are unclear. Several studies have addressed this issue with discrepant results. Recent findings have shown that anemia can lead to cardiovascular and neurological complications, such as congestive heart failure and impaired cognitive function. Objective: To evaluate the hemogram profi le in elderly diabetic patients and compare the same with younger diabetic patients. Materials and Methods: A retrospective chart review of type 2 diabetic patients who participated in clinical trials on diabetes mellitus was carried out. The clinical trials have been approved by the institutional ethics committee. Patient population included both males and females. Patients who underwent baseline hemogram profi le were included for the study. Laboratory parameters collected include hemoglobin, hematocrit value, mean corpuscular volume (MCV), mean corpuscular hemoglobin (MCH), mean corpuscular hemoglobin concentration (MCHC), red cell distribution width (RDW), glycosylated hemoglobin, serum creatinine, and urine albumin. Results: A total of 127 elderly patients with age60 years and 122 patients with age below 60 years were included in the study. Mean hemoglobin concentration in elderly was 13.1 g/dL and in younger patients was 14.8 g/dL. The differences in the hemogram values among the two populations showed statistical signifi cance only for hematocrit (P0.03) and RDW (P  0.002). There was signifi cant positive correlation between hemoglobin level and creatinine clearance (P0.019) and between hemoglobin and urine albumin concentration (P0.035) among elderly patients. Among the elderly patients 25 (19.7%) had anemia (hemoglobin below 12 g/dL), and 18 (14.8%) younger patients had anemia. Chi-square analysis did not show signifi cance for distribution of anemia among the two populations. Conclusion: There was signifi cant difference in the hemogram profi le of elder and younger diabetics; levels were much less in elderly patients.

Item Type: Article
Uncontrolled Keywords: Anemia, diabetes mellitus, elderly, hemogram
Subjects: Medicine > KMC Mangalore > Pharmacology
Medicine > KMC Mangalore > Medicine
Depositing User: KMCMLR User
Date Deposited: 06 Jun 2013 06:22
Last Modified: 06 Jun 2013 06:22
URI: http://eprints.manipal.edu/id/eprint/136242

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