A Comparative Study of Wound Healing in Rats within Wooden and Metallic Pyramid Models

Prabhu, Krishnamoorthi and Rao, Subba BG and Rao, Yeshwanth K (2013) A Comparative Study of Wound Healing in Rats within Wooden and Metallic Pyramid Models. International Journal of Health Sciences and Research, 3 (4). pp. 86-91. ISSN 2249-9571

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Abstract

Introduction: “Wound healing” can be defined as replacement of destroyed tissue by living tissue. The injured tissues are usually replaced by collagen tissue. Wound healing is not an isolated, single phenomenon; but it is a product of the integrated response of several cell types to injury – the end result of which is preservation of life. the present work was done to find out whether wound healing within a “Pyramid Space” is influenced by the material from which the pyramid is made of – by comparing the “wound healing” process in rats within a wooden and metallic (aluminum) pyramid models. Materials and methods: Two pyramid models were used – one of which was made from wood and the other from metal (aluminium) – both of them having same dimensions. The rats kept within the wooden pyramid acted as “control group” and those kept within the metal pyramid as “test group”. Incisional wounds were generated and breaking strength of wound was estimated by continuous, constant water flow technique. Results: Both the groups showed a healthy and abundant granulation tissue, containing numerous capillaries and fusiform fibroblasts. The control animals showed the breaking strength of 381.3 ± 74.1g in the 10 day old incision wound. The “Test Group” animals showed a breaking strength of 376.7 ± 88.1g in the 10 day old wound (p>0.05). Conclusion: This study shows that use of metal pyramid model doesn‟t have any additional benefit in wound healing process – when compared to wooden pyramid model.

Item Type: Article
Uncontrolled Keywords: wound healing; pyramid breaking strength.
Subjects: Medicine > KMC Manipal > Pharmacology
Medicine > KMC Manipal > Physiology
Depositing User: KMC Manipal
Date Deposited: 12 Jun 2013 04:25
Last Modified: 12 Jun 2013 04:25
URI: http://eprints.manipal.edu/id/eprint/136297

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