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The Role of Complement Factors in Neurodegeneration, Neuroinflammation and Neuroprotection: Friend or Foe?

*, Senthil P Kumar and Adhikari, Prabha and *, Jeganathan PS (2012) The Role of Complement Factors in Neurodegeneration, Neuroinflammation and Neuroprotection: Friend or Foe? Indian Journal of Genetics and Molecular Research, 1 (2). pp. 55-56.

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Abstract

Complement is a major component of innate immune system involved in defending against all the foreign pathogens through complement fragments that participate in opsonization, chemotaxis, and activation of leukocytes and through cytolysis by C5b- 9 membrane attack complex. The complement (C) system has been implicated as a factor in the causation or propagation of tissue injury in central and peripheral nervous system disorders. Complement factors play a predominant role in nerve injury, inflammation and repair, thus playing part in neurodegeneration, neuroinflammation and neuroprotection.

Item Type: Article
Uncontrolled Keywords: Immunology; Neuroimmunology; Immunogenetics; Genetic neurology; Complement system.
Subjects: Allied Health > Mangalore Campus > Physiotherapy
Medicine > KMC Mangalore > Physiology
Medicine > KMC Mangalore > Medicine
Depositing User: KMCMLR User
Date Deposited: 21 Jun 2013 10:01
Last Modified: 21 Jun 2013 10:01
URI: http://eprints.manipal.edu/id/eprint/136354

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