Villoglandular papillary adenocarcinoma of cervix associated with cervical intraepithelial neoplasia : a case report and review of literature

Srilatha, PS and Roy, Alfred (2007) Villoglandular papillary adenocarcinoma of cervix associated with cervical intraepithelial neoplasia : a case report and review of literature. Indian Journal of Pathology and Microbiology, 50 (4). pp. 819-821.

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Abstract

Well differentiated villoglandular adenocarcinoma of uterine cervix is a rare tumour which usually occurs in young women. It is considered to be an indolent tumour with favorable prognosis and most of them were treated by conservative procedures. We report a 35 year old lady who came with complaints of 3 months amenorrhoea and an episode of spontaneous bleeding. Urine pregnancy test was negative. Physical examination revealed a cervical polyp. Histopathological findings were consistent with villoglandular papillary adenocarcinoma associated with high grade cervical intraepithelial neoplasia (CIN-3). Left parametrial and left ureteral involvement, proved by biopsy, causing left hydroureteronephrosis was detected. The patient was thus found to be in an advanced stage, stage- III b (FIGO). The patient is currently undergoing radiotherapy. A review of literature showed that only occasional cases showing disease spread have been reported, suggesting caution in the management and regular follow up of the patient.

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