Bairy, KL and Holla, Avinash M and Christopher, Rockson and Sirigiri, Purnima and Kumar, Pawan AV and Chandrashekar, BR and Kumar, Satish MC (2013) Effect of Halobetasol Propionate with Biopolymer on Skin Inflammatory Model in Wistar Rats. Research Journal of Pharmaceutical, Biological and Chemical Sciences, 4 (3). pp. 800-803. ISSN 0975-8585

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Abstract

Various glucocorticoid preparations are used in atopic dermatitis to reduce inflammation. Halobetasol propionate is one such steroid used in atopic dermatitis. There is always a need for better antiflammatory drugs for conditions like atopic dermatitis. A newer formulation is biopolymer based halobetasol propionate .This study was done to compare the efficacy of halobetasol propionate with biopolymer with halobetasol propionate (Halovate) in croton oil ear edema model. In this model, the animals treated with halobetasol propionate with biopolymer showed a significant decrease in inflammation as compared to halobetasol propionate (Halovate). Keywords: Inflammation, halobetasol propionate and halobetasol propionate with biopolymer.

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