The Clinical Management of Hyperemesis Gravidarum

Sonkusare, Shipra (2011) The Clinical Management of Hyperemesis Gravidarum. Archives of Gynecology and Obstetrics, 283. pp. 1183-1192.

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Hyperemesis gravidarum is a severe and disabling condition with potentially life-threatening complications. It is likely to have a multifactorial etiology which contributes to the difficulty in treatment. Treatment is supportive with correction of dehydration and electrolyte disturbance, antiemetic therapy, prevention and treatment of complications like Wernicke’s encephalopathy, osmotic demyelination syndrome, thromboembolism, and good psychological support. There are abundant data on the safety of antihistamines, phenothiazines, and metoclopromide in early pregnancy and treatment should therefore not be withheld on the basis of teratogenicity concerns. Thiamine replacement is indicated in hyperemesis gravidarum to prevent development of Wernicke’s encephalopathy.

Item Type: Article
Uncontrolled Keywords: Nausea and vomiting of pregnancy; Hyperemesis gravidarum; Morning sickness; Wernicke’s encephalopathy; Antiemetics
Subjects: Medicine > KMC Manipal > Obstetrics & Gynaecology
Depositing User: KMC Manipal
Date Deposited: 04 Sep 2013 04:24
Last Modified: 04 Sep 2013 04:24

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