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Microalbuminuria in diabetes mellitus: Association with age, sex, weight, and creatinine clearance

*, Chowta NK and *, Pant P and *, Chowta MN (2009) Microalbuminuria in diabetes mellitus: Association with age, sex, weight, and creatinine clearance. Indian Journal of Nephrology, 19 (2). pp. 53-56. ISSN 0971-4065

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Abstract

Studies in the Western literature show a linear relationship between degree of microalbuminuria and body mass index (BMI), bloodpressure, and duration of diabetes. This study was aimed to determine the correlation of microalbuminuria with age, sex, duration ofdiabetes, BMI, and creatinine clearance in type-2 diabetics in Indian population. One hundred patients (59 males and 41 females)with type-2 diabetes mellitus of duration six months or more and negative for albumin in urine by albustic method were included inthe study. Detailed clinical history was taken followed by a thorough physical examination that included neurological examinationin the selected patients. Micral test was used for estimation of microalbuminuria. Overall prevalence of microalbuminuria in thepresent study was 37%. Among the patients with microalbuminuria, 20 were males and 17 were females. Pearson correlation ofmicroalbuminuria with age showed statistically significant linear relationship. Gender-wise correlation analysis of microalbuminuriafailed to show any statistical significance. Correlation of microalbuminuria with BMI was also not significant (r = 0.063, P > 0.05).Creatinine clearance negatively correlated with microalbuminuria, but this was statistically insignificant. There was a statisticallysignificant correlation of microalbuminuria with duration of diabetes. Prevalence of microalbuminuria is around 37% in type-2diabetes mellitus. Incidence of microalbuminuria increases with age as well as with increased duration of diabetes mellitus. There is no effect of BMI and sex on the prevalence of microalbuminuria.

Item Type: Article
Uncontrolled Keywords: Microalbuminuria, diabetes mellitus, blood pressure, obesity
Subjects: Medicine > KMC Mangalore > Pharmacology
Medicine > KMC Mangalore > Medicine
Depositing User: KMCMLR User
Date Deposited: 23 Sep 2011 06:19
Last Modified: 18 Oct 2011 06:21
URI: http://eprints.manipal.edu/id/eprint/1372

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