Khan, Saleemulla (2010) Evaluation of Wound healing activity of Buxus wallichiana Baill. Asian Journal of Pharmacodynamics and Pharmacokinetics, 10 (1). pp. 59-63. ISSN 1608-2281

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Abstract

Aim:In this study, aim was to investigate the wound healing and antioxidant activities of Buxus wallichiana bark. Meterials and Methods: The Methanolic extract of Buxus walliachiana Baill, was evaluated for wound healing activity by excision model at 5 and 10 % concentration. Results: Methanol extract of Buxus walliachiana ointment (5 %) showed a significant reduction in the wound area from 10th day to 20th day of the experiment and 10 % produced dose depended reduction in the wound area. Nitrofurazolidine ointment (2 %) was used as standard. Methanol extract of Buxus walliachiana ointment 10 % showed significant reduction in wound area when all results were compared with standard. Different extracts of Buxus walliachiana was evaluated for antioxidant potential by; DPPH and Nitric oxide methods. Conclusion: Methanol extract showed potential antioxidant activity.

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