Evaluation of Wound healing activity of Buxus wallichiana Baill

Khan, Saleemulla (2010) Evaluation of Wound healing activity of Buxus wallichiana Baill. Asian Journal of Pharmacodynamics and Pharmacokinetics, 10 (1). pp. 59-63. ISSN 1608-2281

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Aim:In this study, aim was to investigate the wound healing and antioxidant activities of Buxus wallichiana bark. Meterials and Methods: The Methanolic extract of Buxus walliachiana Baill, was evaluated for wound healing activity by excision model at 5 and 10 % concentration. Results: Methanol extract of Buxus walliachiana ointment (5 %) showed a significant reduction in the wound area from 10th day to 20th day of the experiment and 10 % produced dose depended reduction in the wound area. Nitrofurazolidine ointment (2 %) was used as standard. Methanol extract of Buxus walliachiana ointment 10 % showed significant reduction in wound area when all results were compared with standard. Different extracts of Buxus walliachiana was evaluated for antioxidant potential by; DPPH and Nitric oxide methods. Conclusion: Methanol extract showed potential antioxidant activity.

Item Type: Article
Uncontrolled Keywords: Buxus walliachiana;nitrofurazolidine; nitric oxide; wound healing activity.
Subjects: Pharmacy > MCOPS Manipal > Pharmacognosy
Depositing User: KMC Manipal
Date Deposited: 01 Oct 2013 04:05
Last Modified: 01 Oct 2013 04:05
URI: http://eprints.manipal.edu/id/eprint/137338

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