Evaluation of few Marketed products of Salbutamol sulphate syrup IP

Pai, Girish K and Vamshi, Krishna T and Kumar, Lalit and Reddy, Sreenivasa M and Singh, Shreya and Vibha, V (2013) Evaluation of few Marketed products of Salbutamol sulphate syrup IP. Asian Journal of Research in Pharmaceutical Sciences , 3 (3). pp. 114-116. ISSN 2231–5640

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Abstract

The objective of the study was to assess whether few marketed brands of Salbutamol sulphate syrup IP was within the limits as specified in Indian Pharmacopoeia with respect to selected physical parameters. A study was carried out using two different brands coded as brand A and B for Salbutamol sulphate syrup IP. In this study, selected brands were well known brands and a comparative study was planned. Salbutamol is a short acting �2 adrenergic receptor agonist used commonly for the relief of bronchospasm in conditions such as asthma and Chronic Obstructive Pulmonary Disease (COPD). In the present study, three different batches each of brand A and brand B were procured randomly from the medical shop. The tests that were performed included the visual inspection or appearance of product, pH measurement, extractable volume, primary labeling quality and checking of text matter on primary label. From the study, it was found that both the brands were comparable with respect to various physical parameters; however brand B was chosen as best since the results for all three batches were consistent and uniform. Brand A was not user friendly since there was difficulty in opening cap as it is uncomfortable for a patient suffering from asthma. These types of problems sometimes receive market complaints as well.

Item Type: Article
Uncontrolled Keywords: Salbutamol sulphate; COPD; extractable volume; text matter.
Subjects: Pharmacy > MCOPS Manipal > Pharmaceutics
Depositing User: KMC Manipal
Date Deposited: 21 Oct 2013 04:46
Last Modified: 21 Oct 2013 11:02
URI: http://eprints.manipal.edu/id/eprint/137529

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