Invitro Antidiabetic Activity of Pentacyclic Tritrpenoids and Fatty Acid Esters from Bauhinia Purpurea

Gupta, Daksha and Kondongala, Subraya Chandrashekar and Pai, Girish K (2013) Invitro Antidiabetic Activity of Pentacyclic Tritrpenoids and Fatty Acid Esters from Bauhinia Purpurea. International Journal of Pharmacology and Pharmaceutical Technology, 2 (1). pp. 25-28. ISSN 2277-3436

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Abstract

The objective of present work was to evaluate the invitro antidiabetic activity of Pentacyclic tritrpenoids and fatty acid esters from stem bark of Bauhinia purpurea. The samples were studied for their effect on inhibition of glycosylation of haemoglobin, glucose transport across yeast cells and α- Amylase inhibition. Inhibition of glycosylation of haemoglobin and α- Amylase inhibition was in a dose dependent manner and glucose transport differs with the sample and glucose concentration. From the results of the study, it is inferred that, B. purpurea stem bark possesses antidiabetic activity. However, these effects need to be confirmed using in vivo models and clinical trials for its effective utilization as therapeutic agents.

Item Type: Article
Uncontrolled Keywords: Bauhinia purpurea; antidiabetic; Acarbose; Metronidazole.
Subjects: Pharmacy > MCOPS Manipal > Pharmaceutics
Pharmacy > MCOPS Manipal > Pharmacognosy
Depositing User: KMC Manipal
Date Deposited: 26 Oct 2013 10:49
Last Modified: 26 Oct 2013 10:49
URI: http://eprints.manipal.edu/id/eprint/137590

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