Quality of life in HIV/AIDS patients in relation to CD4 count: A cross‑sectional study in Mysore district

Dhar, Murali (2012) Quality of life in HIV/AIDS patients in relation to CD4 count: A cross‑sectional study in Mysore district. International Journal of Health & Allied Sciences, 1 (4). pp. 263-267.

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Background: With the recent advances in clinical tests and treatments for those suffering from HIV/AIDS, the survival of these patients has been increased and their quality of life has become an important focus for researchers and healthcare providers. HIV affects the CD4 cells and CD4 count is the basis on which the ART treatment is started. Objective: To study the relationship of CD4 count with Quality of life of HIV/AIDS patients. Materials and Methods: This cross‑sectional study was done in 255 HIV/AIDS patients at ART center in tertiary care hospital, Mysore. WHO‑QOL‑BREF a summarized quality of life questionnaire was used to assess the Quality of life. CD4 count of each patient was done. Statistical analysis was done using Epi‑info software. To test the significance between QoL score and CD4 count, at test was applied and to see the correlation between QoL score and various domains, Pearson’s correlation co‑efficient was calculated. Results: Out of 255 patients, 149 patients had their CD4 count below 350 with a mean QOL score 50.6 and 106 patients had their CD4 count above 350 with a mean QOL score 55.2. A positive correlation was seen with a r value of 0.31. Patients with higher CD4 count had better QOL than those with lower CD4 counts; thet test showed statistically significant association ( P < 0.05) between CD4 count and QOL. Conclusion: Present study has revealed a strong relationship between QOL and CD4 count of HIV/AIDS patients which necessitates pragmatic interventions to improve the CD4 count

Item Type: Article
Uncontrolled Keywords: Antiretroviral treatment; Human immunodeficiency virus/AIDS; Quality of life and CD4 count
Subjects: Departments at MU > Statistics
Depositing User: KMC Manipal
Date Deposited: 05 Nov 2013 11:03
Last Modified: 05 Nov 2013 11:03
URI: http://eprints.manipal.edu/id/eprint/137649

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