Highly sensitive C-reactive protein in metabolic syndrome

Vidyasagar, Sudha and Razak, Abdul UK and Prashanth, CK and Varma, Muralidhar D and Bairy, KL (2013) Highly sensitive C-reactive protein in metabolic syndrome. Journal, Indian Academy of Clinical Medicine, 14 (3-4). pp. 230-234.

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Abstract

Background: Metabolic syndrome is known to predispose to atherosclerosis. C-reactive protein, a marker of systemic inflammation is significantly associated with the atherosclerotic process. Methods: We prospectively studied the relationship between high-sensitivity C-reactive protein (hs-CRP) with various components of metabolic syndrome in 91 patients with metabolic syndrome at our tertiary care centre in South India. Results: The mean age of patients was 57.5 ± 9.8 years; there were 67 (73.6%) males. On univariate analysis, hs-CRP was found to be significantly increased in patients with diabetes mellitus (p < 0.021) and those with abnormal waist circumference (p<0.003). There was no significant association between hs-CRP and high triglycerides, hypertension, and reduced high density lipoprotein cholesterol. Further, hs-CRP increased significantly with increasing number of components of metabolic syndrome (p< 0.008). Conclusions: Measurement of hs-CRP can be used as a surrogate marker of chronic inflammation in patients with metabolic syndrome.

Item Type: Article
Uncontrolled Keywords: Metabolic syndrome; hs-CRP; India.
Subjects: Medicine > KMC Manipal > Medicine
Medicine > KMC Manipal > Pharmacology
Depositing User: KMC Manipal
Date Deposited: 07 Nov 2013 04:41
Last Modified: 07 Nov 2013 04:41
URI: http://eprints.manipal.edu/id/eprint/137668

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