Synthesis, spectral characterization of Co(II), Ni(II), Cu(II) and Zn(II) complexes of Schiff bases derived from 3-formyl quinoline and 2,6-diaminopyridine and their biological studies

Mutalik, Srinivas (2013) Synthesis, spectral characterization of Co(II), Ni(II), Cu(II) and Zn(II) complexes of Schiff bases derived from 3-formyl quinoline and 2,6-diaminopyridine and their biological studies. Main Group Chemistry, 12 (1). pp. 87-104. ISSN 1024-1221

[img] PDF
Main chemistry.pdf - Published Version
Restricted to Registered users only

Download (157kB) | Request a copy

Abstract

A series of Schiff bases derived from 2-mercapto-3-formyl quinoline/2-hydroxy-3-formyl quinoline with 2,6- diaminopyridine (DAP) and their corresponding transition metal complexes were synthesized, characterized by elemental analysis, spectral (IR, 1H-NMR, Mass, UV-Vis, Fluorescence, ESR, TGA) and magnetic studies. The molar conductances in DMF solution indicated that the complexes were non-electrolytic. The Schiff bases and their metal complexes were screened for analgesic, anti-inflammatory and antipyretic activities. Among all the compounds, the copper complexes had the greatest pharmacological activities.

Item Type: Article
Uncontrolled Keywords: Quinoline; diaminopyridine; coordination; antipyretic; analgesic; anti-inflammatory.
Subjects: Pharmacy > MCOPS Manipal > Pharmaceutics
Depositing User: KMC Manipal
Date Deposited: 11 Nov 2013 04:14
Last Modified: 11 Nov 2013 04:14
URI: http://eprints.manipal.edu/id/eprint/137687

Actions (login required)

View Item View Item