Clinical Spectrum of Rheumatic Fever and Rheumatic Heart Disease: A 10 Year Experience in an Urban Area of South India

Joseph, Nitin and Madi, Deepak and *, Ganesh S Kumar and *, Maria Nelliyanil and Saralaya, Vittal and Rai, Sharada (2013) Clinical Spectrum of Rheumatic Fever and Rheumatic Heart Disease: A 10 Year Experience in an Urban Area of South India. North American Journal of Medical Sciences, 5 (11). pp. 647-652.

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Background: Rheumatic fever (RF) is an important problem concerning developing countries like India. Rheumatic heart disease (RHD) is one of the most readily preventable chronic diseases. Aim: This study was done to find out the clinical profile, risk factors, compliance with treatment and outcome among RF/RHD cases so as to suggest better case management strategies. Materials and Methods: Clinical records of 51 RF and 71 RHD cases admitted in tertiary care hospitals in Mangalore between 2001 and 2010 were reviewed retrospectively. Results: Mean age of RF cases were 17.4 ± 12.1 years and RHD cases were 33.2 ± 18.6 years. More than half of RF and RHD cases were males. Commonest risk factors among RF cases were poor socioeconomic status (60.4%), history of upper respiratory tract infection before disease onset (58.8%) and undernutrition (35.3%). Commonest clinical manifestation among RF cases was fever 39 (76.5%) followed by polyarthritis 34 (66.7%). Commonest valvular lesions among RHD cases was mitral stenosis with mitral regurgitation found in 42.9% cases. Compliance of patients with prophylactic antibiotics was found to be 37 (30.3%). Mortality rate was significantly more among RHD cases (P = 0.0399). Conclusions: Improvement of socioeconomic and nutritional factors is an important task required for primary prophylaxis and of compliance for secondary prophylaxis of RF.

Item Type: Article
Uncontrolled Keywords: Clinical features, Compliance, Rheumatic fever, Rheumatic heart disease, Risk factors, Valvular lesions
Subjects: Medicine > KMC Mangalore > Obstetrics & Gynaecology
Medicine > KMC Mangalore > Pathology
Medicine > KMC Mangalore > Community Medicine
Medicine > KMC Mangalore > Medicine
Depositing User: KMCMLR User
Date Deposited: 02 Dec 2013 06:23
Last Modified: 02 Dec 2013 06:23

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