Optical Pathology of Oral Tissue: A Raman Spectroscopy Diagnostic Method

Venkatakrishna, K and Kurien, Jacob and Pai, Keerthilatha M and Valiathan, Manna and Kumar, Nirmala Nagesh and Murali Krishna, C and Ullas, G and Kartha, VB (2001) Optical Pathology of Oral Tissue: A Raman Spectroscopy Diagnostic Method. CURRENT SCIENCE, 80 (5). pp. 665-669.

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Raman and fluorescence spectroscopy methods are being considered as techniques which could be complementary or even alternative to biopsy, and pathology and clinical assays in many medical applications. The present paper discusses the results of Raman spectral studies on oral tissues for optical pathology. It is shown that Raman spectra of oral tissues can be classified into spectra of normal and malignant sets and a model based on such a classification can be used to analyse oral tissue for detection of oral malignancy. Sensitivity and specificity calculated from 90 test spectra are better than 85 and 90 per cent respectively.

Item Type: Article
Subjects: Dentistry > MCODS Manipal > Oral Medicine and Radiology
Dentistry > MCODS Manipal > Oral Pathology and Microbiology
Life Sciences > MLSC Manipal
Medicine > KMC Manipal > Pathology
Medicine > KMC Manipal > Radiotherapy and Oncology
Depositing User: KMC Manipal
Date Deposited: 30 Sep 2011 06:25
Last Modified: 18 Oct 2013 04:28
URI: http://eprints.manipal.edu/id/eprint/1380

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