Study of the clinicopathological profile of paediatric haematological malignancies at a tertiary care centre

Hegde, Shruti S and * , Soundarya Mahalingam and *, Harsha K (2013) Study of the clinicopathological profile of paediatric haematological malignancies at a tertiary care centre. Journal of Evolution of Medical and Dental Sciences, 2 (43). pp. 8439-8443.

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Abstract

Introduction: Leukaemia’s (Acute Lymphocytic Leukaemia i.e., ALL, Acute Myeloblastic Leukaemia i.e., AML and Burkitt’s) are common during childhood. There are very few studies in recent past correlating the symptoms and laboratory findings to the specific types of acute leukaemia’s Indian population. OBJECTIVE: The present study was aimed at analysing the presenting features, laboratory findings in correlation with the final diagnosis as determined by the flow cytometric analysis. STUDY DESIGN: Retrospective Study, STUDY SETTING: Tertiary care hospital. PARTICIPANT: Children who were diagnosed to have leukemia. METHODS: The Performa was used to record the clinical & pathological profile. RESULTS: ALL was found to be the most common type of haematological malignancy in children. Among the ALL, B-Cell formed the majority and 92.3% of B-cell ALL were CALLA positive. Fever was found to be the most common symptom and pallor the most common sign. The most common site of extramedullary involvement was found to be the spleen. Anaemia and thrombocytopenia was found in majority of the cases. All cases had hypercellular marrow at the time of diagnosis.

Item Type: Article
Subjects: Medicine > KMC Mangalore > Paediatrics
Medicine > KMC Mangalore > Community Medicine
Depositing User: KMCMLR User
Date Deposited: 24 Dec 2013 09:54
Last Modified: 24 Dec 2013 09:54
URI: http://eprints.manipal.edu/id/eprint/138012

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