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Prevalence of vitamin D deficiency and its relationship with subclinical hypothyroidism

*, Sudha K and Hegde, Anupama and Manjrekar, Poornima and *, Reshma Kumarachandra (2013) Prevalence of vitamin D deficiency and its relationship with subclinical hypothyroidism. International Journal of Pharma and Bio Sciences, 4 (4). (B) 1380-(B) 1384. ISSN 0975-6299

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Abstract

Vitamin D deficiency has been implicated in various diseases including cancer and auto immune diseases. The present study attempts to establish a relation between vitamin D deficiency, thyroid hormones and TSH in subclinical hypothyroidism.100 newly diagnosed patients with subclinical hypothyroidism were divided into three groups according to vitamin D levels. Mean plasma TSH and T3 values decreased with increasing vitamin D values and T4 increased with increasing vitamin D tertiles. However , intergroup comparison showed no statistically significant changes .In females, negative correlation between vitamin D and TSH was statistically significant (p=0.014).The prevalence of vitamin D deficiency, insufficiency and sufficiency in 100 patients was found to be 38%, 38% and 24%. The study indicates the prevalence of vitamin D deficiency in subclinical hypothyroidism, but further studies are needed to determine whether it is a causative factor in the pathogenesis of the disease or a consequence.

Item Type: Article
Uncontrolled Keywords: Vitamin D, thyroid hormones, subclinical hypothyroidism
Subjects: Medicine > KMC Mangalore > Biochemistry
Depositing User: KMCMLR User
Date Deposited: 01 Jan 2014 07:17
Last Modified: 01 Jan 2014 07:17
URI: http://eprints.manipal.edu/id/eprint/138190

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