Setty, Manjunath M and Gupta, Nilesh and Lobo, Richard and Khan, Saleemulla and Sreedhara, CS (2013) Anthelmintic Activity of Alcoholic and Aqueous Extract of Anisochiluscarnosus (Wall). Research Journal of Pharmaceutical, Biological and Chemical Sciences, 4 (4). pp. 1666-1670. ISSN 0975 - 8585

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Abstract

The present investigation was undertaken to evaluate the anthelmintic activity of ethanolic and aqueous leaf extracts of Anisochiluscarnosus , using Indian earthworm Pheretima posthuma .Three different concentrations (50, 25 and 12.5 mg/ml) of each of ethanolic and aqueous extract was used for bioassay, which involved determination of time of paralysis (TP ) and time of death (T D ) of the worms. 1% gum acacia in saline solution and Mebendazole (15mg/ml) were used as control and standard respectively in the study. The results obtained in the present study indicated potential activity ata concentration of 50mg/mlof the crude ethanolic extract when compared to reference standard Mebendozole in terms of T P and T D .To conclude, the leaves of Anisochiluscarnosus can be used as a natural anthelmintic however, advanced studies on the plant can reveal the active principles responsible for the activity.

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