Carcinomatous meningitis in a gastric adenocarcinoma - A case report

Rao, Purnima S and Minal , Jessica and Pooja , Suresh K (2013) Carcinomatous meningitis in a gastric adenocarcinoma - A case report. International Journal of Medical and Applied Sciences, 2 (4). pp. 342-345. ISSN 2320‐3137

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Abstract

Gastric carcinoma is the third most common malignancy in the gastrointestinal tract. Unusual sites of tumor metastases are seen with the present advancement in cancer therapeutics. Gastric carcinoma metastasis to cerebrospinal fluid is one such unusual site. We report a case of carcinomatous meningitis in a gastric carcinoma, an unusual involvement. 57 year old male came with complaints of weight loss and loss of appetite since 2 months. An upper gastrointestinal endoscopy showed an ulceroproliferative growth at the pylorus with stasis of food. Biopsy was taken and it was reported as poorly differentiated adenocarcinoma. Following this, the tumor was resected and a feeding jejunostomy was done. On the 4th post op day, the patient complained of headache, nausea, vomiting and became drowsy. A diagnostic cerebrospinal fluid (CSF) tap was done which showed malignant cells. MRI showed diffuse meningeal enhancement. Intrathecal chemotherapy was planned; however patient worsened further and succumbed to illness on the 10th post op day.

Item Type: Article
Uncontrolled Keywords: Carcinomatous meningitis, Gastric carcinoma, Adenocarcinoma, Cerebrospinal fluid
Subjects: Medicine > KMC Mangalore > Pathology
Depositing User: KMCMLR User
Date Deposited: 09 Jan 2014 11:00
Last Modified: 09 Jan 2014 11:00
URI: http://eprints.manipal.edu/id/eprint/138296

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