Asymptomatic bacteriuria among patients with diabetes mellitus at a tertiary care center

Vishwanath, Shashidhar and Sarda, Radhika and D’Souza, Annet and Mukhopadhyay, Chiranjay (2013) Asymptomatic bacteriuria among patients with diabetes mellitus at a tertiary care center. National Journal of Laboratory Medicine, 2 (3). pp. 16-19.

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Abstract

Objective: Patients with diabetes mellitus have a higher prevalence of asymptomatic bacteriuria and incidence of urinary tract infections compared to patients without diabetes mellitus. A prospective pilot study was conducted to determine the frequency of association of asymptomatic bacteriuria among patients with diabetes mellitus in comparison to control group without diabetes mellitus. Methods: Urine specimens were processed by microscopy and culture following standard guidelines. The spectrum of uro-pathogens causing asymptomatic bacteriuria and their antibiotic susceptibility profile were noted. Results: Asymptomatic bacteriuria was seen more commonly in patients with diabetes mellitus (4%) than in healthy control subjects. Asymptomatic bacteriuria was not seen in the non-diabetic individuals under control group. Three out of the four patients with asymptomatic bacteriuria had associated complications of diabetes mellitus. Enterococcus faecalis (2,50%), Staphylococcus saprophyticus (1, 25%) and Escherichia coli (1, 25%) were the organisms isolated from patients with asymptomatic bacteriuria. Staphylococcus saprophyticus isolate was mostly sensitive to antimicrobials tested. Enterococcus faecalis was sensitive to ampicillin. Escherichia coli isolate was multi-drug resistant. Conclusion: Asymptomatic bacteriuria was more common among patients with diabetes mellitus than in healthy control subjects. Further, long term studies investigating the occurrence of complications secondary to asymptomatic bacteriuria in patients with diabetes mellitus and randomized control studies for studying the efficacy of antimicrobial therapy in preventing further complications in diabetes mellitus patients in Indian setups are needed.

Item Type: Article
Uncontrolled Keywords: Bacteriuria; diabetes mellitus; enterococcus faecalis; escherichia coli; staphylococcus saprophyticus.
Subjects: Medicine > KMC Mangalore > Microbiology
Depositing User: KMC Manipal
Date Deposited: 17 Jan 2014 06:53
Last Modified: 17 Jan 2014 07:04
URI: http://eprints.manipal.edu/id/eprint/138424

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