Preparation and characterization of biodegradable scaffolds of poly(lactideco- glycolide) 50:50 and hydroxyapatite for dental applications

Ginjupalli, Kishore and Bhat, Mahalinga K and Udupa, N (2014) Preparation and characterization of biodegradable scaffolds of poly(lactideco- glycolide) 50:50 and hydroxyapatite for dental applications. Composite Interfaces, 21 (1). pp. 31-44.

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Abstract

In the present study, biodegradable scaffolds of poly (lactide-co-glycolide) PLGA 50:50 with acidic microclimate controlling additives were prepared and characterized for their degradation behavior, physical, and mechanical properties. Results indicate that scaffolds with acidic microclimate controlling additives undergo degradation without large variation in pH of the surrounding medium. Results also indicated that microclimate controlling additives did not significantly alter the physical and mechanical properties of the scaffolds. From the results, it can be concluded that PLGA 50:50 scaffolds with acidic microclimate controlling additives can be used as root replicas after the tooth extraction.

Item Type: Article
Uncontrolled Keywords: Alveolar bone resorption; tooth extraction; biodegradable composites; scaffolds; poly(lactide-co-glycolide); hydroxyapatite.
Subjects: Dentistry > MCODS Manipal > Dental Materials
Dentistry > MCODS Manipal > Periodontology
Pharmacy > MCOPS Manipal > Pharmacy Management
Depositing User: KMC Manipal
Date Deposited: 29 Jan 2014 11:22
Last Modified: 29 Jan 2014 11:22
URI: http://eprints.manipal.edu/id/eprint/138579

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