Plasmodium vivax remains responsive to chloroquine with primaquine treatment regimen: a prospective cohort study from tertiary care teaching hospital in southern India

Saravu, Kavitha and Acharya, Vasudeva and Kumar, Krishna and Kumar, Rishikesh (2012) Plasmodium vivax remains responsive to chloroquine with primaquine treatment regimen: a prospective cohort study from tertiary care teaching hospital in southern India. Tropical Doctor, 42 (3). pp. 1-2.

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Abstract

We conducted this prospective study among 110 symptomatic Plasmodiumvivax patients attending the Kasturba Hospital,Manipal, India, in order to evaluate their clinico-laboratory profile duringJuly 2007^July 2009. Complications observed among patients were: anaemia (46.4%; 95% confidence interval [CI], 37.08^55.72%); thrombocytopenia (68.2%;95%CI,59.5^76.9%); leucopenia (29.1%; 95% CI, 20.61^37.59%); hyperbilirubinaemia (20%; 95% CI,12.53 ^ 27.47%); non-oliguric renal failure (10.9%; 95% CI, 5.08^16.72%); elevated serumtransaminases (33.6%; 95% CI, 24.77^ 42.43%); hypotension (8.2%;95% CI, 3.07^13.33%); hepatomegaly (27.3%;95% CI,18.97^35.63%); and splenomegaly and jaundice in12.7% (95% CI, 6.48^ 18.92%).The 99% chloroquine response and zeromortality observed in this study of vivaxmalaria are encouraging points for practicing physicians.

Item Type: Article
Subjects: Medicine > KMC Manipal > Medicine
Depositing User: KMC Manipal
Date Deposited: 30 Jan 2014 10:28
Last Modified: 30 Jan 2014 10:28
URI: http://eprints.manipal.edu/id/eprint/138593

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