Retrospective correlation of fasting glucose and glycated hemoglobin with serum electrolytes, urea and creatinine in diabetic patients

Choudhry, Afreen Arshad and Rajeshwari, SG and Gururaja, Arpitha and Prabhu, Krishnananda and Ravishankar, N (2014) Retrospective correlation of fasting glucose and glycated hemoglobin with serum electrolytes, urea and creatinine in diabetic patients. Asian Pacific Journal of Tropical Disease, 4 (Supl-1). S385-S388.

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Abstract

Objective: To assess the relationship of fasting blood glucose and glycated serum electrolytes i.e. sodium and potassium, urea and creatinine in patie nhtse mwoigthlo dbiianb wetieths mellitus for at least a period of ten years. Methods: One hundred and forty diabetic individuals between the age group 45-70 who were diabetic since at least past 10 years and visited the outpatient department at Kasturba Hospital, sMeacntiiponal.. All the data were obtained from the Kasturba Medical College and Hospital records method Potassium and sodium levels were estimated by ion selective electrodes indirect urease m(Cetohboads a6n0d0 0s).e rFuamst icnrge agtilnuicnoes ebsy were estimated by hexokinase method, serum urea by estimated by ion exchange chromatographJayf fues'isn gm ethod (Cobas 6000). Glycated hemoglobins were HPLC Variant II Turbo. Results: The association between sodium with glycated Hb and sodium with fasting glucose is ipnovtaesrssieulym rweliathte fda satinndg tghleuicro saes,s oucreiaat iwoint hw fearseti nsgta gtilsutcicoaslel ya nsdig cnriefiactainnitn. eT wheit ha sfasostciinagt igolnu cboestew weeans found to be statistically insignificant. Conclusions: Hyperglycaemic hyperosmolar state in diabetes may influence the levels of various serum analytes such as sodium, potassium, urea and creatinine due to dilutional effects. Hence before interpretation of these results, it is suggessted that they have to be correlated with serum/urine osmolarity levels.

Item Type: Article
Uncontrolled Keywords: Diabetes mellitus; Dilutional hyponatremia; Osmotic diuresis; Glycated hemoglobin.
Subjects: Medicine > KMC Manipal > Biochemistry
Departments at MU > Statistics
Depositing User: KMC Manipal
Date Deposited: 10 Feb 2014 05:09
Last Modified: 10 Feb 2014 05:09
URI: http://eprints.manipal.edu/id/eprint/138738

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