Study of clinical characteristics and treatment pattern of scrub typhus in tertiary care hospital

Inamdar, Shirish and Thunga, Girish and Acharya, Raviraja and Vijayanarayana, K and Shridharan, N and Bhrugu, P (2013) Study of clinical characteristics and treatment pattern of scrub typhus in tertiary care hospital. Journal of Pharmaceutical Sciences and Research, 5 (5). pp. 107-110. ISSN 0975-1459

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Abstract

Scrub typhus is an endemic disease in many parts of India and is mainly caused by the rickettsial bacteria Orientia tsutsugamushi. It is associated with several complications and has emerged as one of the leading public health problems in recent times. This study describes the clinical profile of 200 scrub typhus positive cases admitted in a tertiary care hospital. The complete clinical profiles of the patients were collected in a suitable designed profile form. Out of 200 cases 80 were females and 120 were males. Fever was the chief complaints during the admission followed by headache, hepatosplenomegaly, abdominal pain and lymphadenopathy. Eschar was present in 75.5% of the admitted cases and was more in males (59%). Liver enzymes were elevated in almost all the patients (95%). Acute Respiratory Distress Syndrome (ARDS), sepsis, meningoenchephilitis, diabetes, Pneumonia, urinary tract infection, candidiasis were the most common complications observed in the study population. All cases were successfully treted with doxycycline. Report emphasizes the fact that a diagnosis of scrub typhus should be suspected when a patient presents with fever and laboratory evidence of liver dysfunction for the early detection of the disease which could help in reduce mortality.

Item Type: Article
Uncontrolled Keywords: Rickettsial; Eschar; ARDS; liver enzymes.
Subjects: Medicine > KMC Manipal > Medicine
Pharmacy > MCOPS Manipal > Pharmacy Practice
Depositing User: KMC Manipal
Date Deposited: 12 Feb 2014 04:28
Last Modified: 12 Feb 2014 04:28
URI: http://eprints.manipal.edu/id/eprint/138790

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