Pure Red Cell Aplasia Following Thymothymectomy: A Case Report

Manohar, Chethan and Nayal, Bhavna and Rao, Anuradha CK (2013) Pure Red Cell Aplasia Following Thymothymectomy: A Case Report. Malaysian Journal of Medical Sciences, 20 (5). pp. 83-85.

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Thymoma, a rare epithelial neoplasm, is the most common anterior-superior mediastinal tumour. Thymoma can occur sporadically or in association with other conditions, such as myasthenia gravis, pure red cell aplasia (PRCA), and hypogammaglobulinemia. Only 5% of thymoma cases develop PRCA; however, 10–50% of patients presenting with PRCA have an associated spindle cell type thymoma. Thymoma complicated by PRCA is associated with a poor outcome. We report the case of a 38-year-old female who presented with chest pain, and was diagnosed with an anterior mediastinal mass. A thymectomy was performed, and histopathological examination revealed mixed thymoma; two months later, the patient developed PRCA. The present case reinforces the need for clinicians to be vigilant with thymoma patients, even following thymectomy.

Item Type: Article
Uncontrolled Keywords: Erythropoiesis; Mediastinum; Pure red cell aplasia; Thymoma
Subjects: Medicine > KMC Manipal > Pathology
Depositing User: KMC Manipal
Date Deposited: 06 Mar 2014 06:46
Last Modified: 06 Mar 2014 06:46
URI: http://eprints.manipal.edu/id/eprint/139016

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