Primary Amoebic meningoencephalitis in an infant due to naegleria fowleri

Khanna, Vinay and Khanna, Ruchee and Hebbar, Shrikiran and Shashidhar, V and Mundkur, Suneel C and Munim, Frenil and Annamalai, Karthick and Nayak, Deepak M and Mukhopadhayay, Chiranjay (2011) Primary Amoebic meningoencephalitis in an infant due to naegleria fowleri. Case Reports in Neurological Medicine, 2011. pp. 1-3.

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Primary amoebic meningoencephalitis (PAM) caused by free-living amebae Naegleria fowleri is a rare and fatal condition. A fatal case of primary amoebic meningoencephalitis was diagnosed in a 5-month-old infant who presented with the history of decrease breast feeding, fever, vomiting, and abnormal body movements. Trophozoites of Naegleria fowleri were detected in the direct microscopic examination of CSF and infant was put on amphotericin B and ceftazidime. Patient condition deteriorated, and he was discharged against medical advice and subsequently expired. We also reviewed previously reported 8 Indian cases of primary amoebicmeningoencephalitis (PAM) and observed that for the last 5 years, none of the patients responded to amphotericin B. Has an era of amphotericin B-resistant Naegleria fowleri been emerged? Management strategy of PAM needs to be reviewed further.

Item Type: Article
Subjects: Medicine > KMC Manipal > Microbiology
Medicine > KMC Manipal > Pathology
Medicine > KMC Manipal > Paediatrics
Depositing User: KMC Manipal
Date Deposited: 22 Mar 2014 09:25
Last Modified: 22 Mar 2014 09:25

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