Development of Carrageenan based Nanogel as Vehicle for Drug Release

Singh, Surabhi and Thakur, Goutam (2014) Development of Carrageenan based Nanogel as Vehicle for Drug Release. In: MUSRF- SRPC-2014 , 11-12,2014 , Manipal, India.

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Abstract

The design and preparation of nanogel have attracted interest in drug delivery system because of their properties, which are tuneable particle size, increased stability, faster dissolution rate and release of drug. Moreover, it also improves the delivery of poorly soluble drugs in aqueous media. The present work highlights the design of gels with different concentration of carrageenan polymers for drug delivery, whose particle size could be exploited in the nano scale. Reverse micro-emulsion technique has been used for gel synthesis. After synthesis, gels are use to explore their particle size, zeta potential, Fourier Transform Infrared Spectroscopy(FTIR) characterization which is required for further evaluation of drug encapsulation & release efficiency. It was found that the average particle size of sample falls near the desired range. The sample’s zeta potential is also good and therefore could be used for further studies. However in other samples the particle size was found to be much greater than expected. Future work will be directed towards reducing the particle size to the desired range.

Item Type: Conference or Workshop Item (Paper)
Subjects: Engineering > MIT Manipal > Biomedical
Depositing User: MIT Library
Date Deposited: 16 Apr 2014 07:00
Last Modified: 16 Apr 2014 07:00
URI: http://eprints.manipal.edu/id/eprint/139365

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