Glutaraldehyde cross-linked chitosan-PVA composite films: a promising candidate for wound healing management

Panchal, Ruchira and Thakur, Goutam (2014) Glutaraldehyde cross-linked chitosan-PVA composite films: a promising candidate for wound healing management. In: MUSRF- SRPC-2014 , 11-12,2014 , Manipal, India.

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Abstract

In the present study an attempt has been made to develop bio polymeric composite films using polyvinyl alcohol (PVA) and chitosan. Given to their excellent biocompatibility and degradable nature, composite films were exploited for wound healing application. Solvent casting method was used to prepare the thin films. Different concentrations of the Films were prepared varying the proportion of chitosan and PVA and cross-linked with glutaraldehyde owing to improve the stability of the structural moiety. Characterization studies were carried out by Fourier Transform Infrared Spectroscopy (FTIR) and swelling studies. Results suggest that the cross-linked films being compact influence swelling than the uncross-linked counterpart. FTIR studies indicated chemical interaction occurred at varied combination of the polymers used. Water uptake properties of the composites were compared and indicate that the films could be tuned for wound healing management.

Item Type: Conference or Workshop Item (Paper)
Subjects: Engineering > MIT Manipal > Biomedical
Depositing User: MIT Library
Date Deposited: 21 Apr 2014 10:46
Last Modified: 16 May 2014 09:24
URI: http://eprints.manipal.edu/id/eprint/139404

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