Anticancer Evaluation of some of the Novel Iminoflavones

Jayashree, BS and Kawade, Shishir and Venkatachalam, H (2014) Anticancer Evaluation of some of the Novel Iminoflavones. Research Journal of Chemistry and Environment, 18 (1). pp. 32-40.

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Abstract

Flavonoids recovered from plant extracts have been well known to exhibit wide variety of biological activities and it is worth mentioning their antiproliferative effects on various cancer cell lines.To support this, several synthetic flavonoids are reported for their antioxidant activity and anticancer activity. Based on our earlier study, we attempted to modify the flavones and chalcones to their corresponding thio and imino compound by isosterically replacing the oxygen of the carbonyl functional group with sulphur atom. The newly synthesized test compounds were screened for in vitro antioxidant and anticancer activities.

Item Type: Article
Uncontrolled Keywords: Anticancer; Antioxidant; Chalcones; Imino-flavones; Evaluation
Subjects: Health Sciences > KMCIC
Pharmacy > MCOPS Manipal > Pharmaceutical Chemistry
Depositing User: KMC Manipal
Date Deposited: 07 May 2014 04:30
Last Modified: 07 May 2014 04:30
URI: http://eprints.manipal.edu/id/eprint/139483

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