Frequency and Intensive Care Related Risk Factors of Pneumothorax in Ventilated Neonates

Bhat, Ramesh Y and Ramdas, Vidya (2014) Frequency and Intensive Care Related Risk Factors of Pneumothorax in Ventilated Neonates. Pulmonary Medicine (2014). pp. 1-5.

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Abstract

Objectives . Relationships of mechanical ventilation to pneumothorax in neonates and care procedures in particular are rarely studied. We aimed to evaluate the relationship of selected ventilator variables and risk events to pneumothorax.Methods. Pneumothorax was defined as accumulation of air in pleural cavit y as confirmed by chest radiograph. Relationship of ventilator mode, selected settings, and risk procedures prior to detection of pneumothorax was studied using matched controls. Results .Of 540 neonates receiving mechanical ventilation, 10 (1.85%) were found to have pneumothorax. Respiratory distress syndrome, meconiumaspirationsyndrome, and pneumoniaweretheunderlyinglungpathology.Pneumothoraxmostly(80%)occurredwithin 48 hours of life. Among ventilated neonates, significantly higher percentage with pneumothorax received mandatory ventilation than controls (70% versus 20%; 푃 < 0.01 ). Peak inspiratory pressure > 20cm H 2 O and overventilation were not significantly associated with pneumothorax. More cases than controls underwent care procedures in the preceding 3 hours of pneumothorax event. Mean airway pressure change ( 푃=0.052 ) and endotracheal suctioning ( 푃=0.05 ) were not significantly associated with pneumothorax. Reintubation ( 푃=0.003 ), and bagging ( 푃=0.015 ) were significantly associated with pneumothorax. Conclusion . Pneumothorax among ventilated neonates occurred at low frequency. Mandatory ventilation and selected care procedures in the preceding 3 hours had significant association.

Item Type: Article
Subjects: Medicine > KMC Manipal > Paediatrics
Depositing User: KMC Manipal
Date Deposited: 30 May 2014 06:07
Last Modified: 30 May 2014 06:07
URI: http://eprints.manipal.edu/id/eprint/139599

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