Bhat, Ramesh Y and Kumar, Pavan CG (2014) Sixth hour Transcutaneous Bilirubin Predicting Significant Hyperbilirubinemia in ABO Incompatible Neonates. World Journal of Pediatrics , 10 (2). pp. 182-185.
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Abstract
Background: Neonates with ABO hemolytic disease are at greater risk for developing significant hyperbilirubinemia. We aimed to determine whether sixth hour transcutaneous bilirubin (TcB) could predict such a risk. Methods: TcB measurements were obtained at the 6th hour of life in blood group A or B neonates born to blood group O, rhesus factor compatible mothers. Subsequent hyperbilirubinemia was monitored and considered significant if a neonate required phototherapy/exchange transfusion. The predictive role of sixth hour TcB was estimated. Results: Of 144 ABO incompatible neonates, 41(OA, 24; O-B, 17) had significant hyperbilirubinemia.Mean sixth hour TcB was significantly higher among neonates who developed significant hyperbilirubinemia than those who did not (5.83±1.35 mg/dL vs. 3.65±0.96 mg/dL, P<0.001). Sixth hour TcB value >4 mg/dL had the highest sensitivity of 93.5% and >6 mg/dL had the highest specificity of 99%. Area under receiver operating characteristic curve was 0.898. Conclusion: Sixth hour Tc B predicts subsequent significant hyperbilirubinemia in ABO incompatible neonates.
Item Type: | Article |
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Uncontrolled Keywords: | ABO incompatibility; Neonate; Phototherapy; Significant hyperbilirubinemia; Transcutaneous bilirubin |
Subjects: | Medicine > KMC Manipal > Paediatrics |
Depositing User: | KMC Manipal |
Date Deposited: | 04 Jun 2014 10:24 |
Last Modified: | 04 Jun 2014 10:24 |
URI: | http://eprints.manipal.edu/id/eprint/139649 |
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