A Novel Subtype of Myeloproliferative Disorder? JAK2V617F-associated Hypereosinophilia with Hepatic Venous Thrombosis

Dasari, Sowjanya and Naha, Kushal and Hande, Manjunath H and Vivek, G (2013) A Novel Subtype of Myeloproliferative Disorder? JAK2V617F-associated Hypereosinophilia with Hepatic Venous Thrombosis. BMJ Case Report. pp. 1-3.

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Abstract

We report the case of a 27-year-old man, presenting with one episode of massive haematemesis and a history of persistent eosinophilia for the past 8 months. An evaluation revealed hepatic cirrhosis with portal hypertension, secondary to chronic Budd-Chiari syndrome. Further investigations confirmed a diagnosis of hypereosinophilic syndrome. Molecular genetic analysis was negative for FIP1L1-PDGFRA gene rearrangement, but positive for JAK2V617F mutation.

Item Type: Article
Subjects: Medicine > KMC Manipal > Cardiology
Medicine > KMC Manipal > Medicine
Depositing User: KMC Manipal
Date Deposited: 10 Jun 2014 11:20
Last Modified: 10 Jun 2014 11:20
URI: http://eprints.manipal.edu/id/eprint/139696

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