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Rheumatoid arthritis in the elderly and its relationship with periodontitis: A review

Agnihotri, Rupali and Gaur, Sumit (2014) Rheumatoid arthritis in the elderly and its relationship with periodontitis: A review. Geriatrics Gerontology International, 14. pp. 8-22.

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Abstract

Periodontitis and rheumatoid arthritis are chronic inflammatory diseases commonly seen in the elderly. It has been proposed that the two conditions are interrelated and influence the severity of each other. Recently, the role of Porphyromonas gingivalis, a periodontopathogen, has been explained in the pathogenesis and progression of rheumatoid arthritis. It can be inferred from the present review that the two conditions share a common pathobiology, genetics and environmental risk factors. Furthermore, a thorough understanding of the aforementioned mechanisms might enable the development of conjoint treatment modalities beneficial in treating the geriatric population afflicted by both the disorders.

Item Type: Article
Uncontrolled Keywords: Citrullination; geriatrics; host response; periodontitis; rheumatoid arthritis.
Subjects: Dentistry > MCODS Manipal > Pedodontics and preventive Dentistry
Dentistry > MCODS Manipal > Periodontology
Depositing User: KMC Manipal
Date Deposited: 20 Jun 2014 04:36
Last Modified: 20 Jun 2014 04:36
URI: http://eprints.manipal.edu/id/eprint/139843

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