Rai, Padmalatha S (2013) Antibacterial Activity of Leaf Extracts of Adhatoda vasica. International Journal of Biomedical and Pharmaceutical Sciences, 7 (1). pp. 45-47.

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Abstract

The present study aimed to evaluate the in vitro antimicrobial activity of pharmacologically important Adhatoda vasica plant extracts against Pseudomonas aeruginosa, Klebsiella pneumoniae, Staphylococcus aureus and Salmonella typhi.The agar well diffusion method was adopted to determine antibacterial activity against all the tested microorganisms. The selection of extracts was based on a phytochemical screening for the presence of secondary metabolites. The methanolic extract of A. vasica showed a maximum zone of inhibition (18.17 ± 0.44 mm) for S. aureus and was effective against all bacterial strains tested, thus showing antimicrobial activity. The methanolic extract of the leaves was stronger than extracts based on other solvents such as chloroform and hexane, which showed moderate to weak activity, respectively.

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