Hepatoprotective properties of boerhavia diffusa and aerva lanata against carbon tetra chloride induced hepatic damage in rats

Rai, Padmalatha S (2011) Hepatoprotective properties of boerhavia diffusa and aerva lanata against carbon tetra chloride induced hepatic damage in rats. Pharmacologyonline, 3. pp. 435-441. ISSN 1827-8620

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Abstract

The petroleum ether extract, methanolic extracts and isolated compounds of B. diffusa and A. lanata were subjected to pharmacological screening on mice models. All the extracts obtained showed hepatoprotective activity in albino rats where the hepatotoxicity was induced by administering CCl4. Animals treated with doses of 100, 200 and 300mg/kg, of plant extracts, it showed a significant protection of liver histologically and serum tests after the last doses of CCl4. Thus the current study reveals that plant extracts from the plants B. diffusa and A. lanata have significant hepatoprotective property.

Item Type: Article
Uncontrolled Keywords: Plant extract; herbal medicine; liver toxicity.
Subjects: Life Sciences > MLSC Manipal
Depositing User: KMC Manipal
Date Deposited: 20 Jun 2014 10:03
Last Modified: 20 Jun 2014 10:03
URI: http://eprints.manipal.edu/id/eprint/139857

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