Evaluation of antidiabetic and antipyretic activity of butea monosperma (lam) extracts on rats

Rai, Padmalatha S (2012) Evaluation of antidiabetic and antipyretic activity of butea monosperma (lam) extracts on rats. International Journal of Preclinical and Pharmaceutical Research, 3 (2). pp. 73-78. ISSN 2229 7502

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Abstract

In the present investigation an indigenous medicinal plant species of the Western Ghats Butea monosperma were selected to explore its morphogenic potentialities under in vitro condition, to isolate active constituents from different plant part extracts and to evaluate pharmacological properties of the crude and isolated constituents for antipyretic, antidiabetic, disorders. The antipyretic potential of B. monosperma was evaluated using yeast induced pyrexia on Albino rats and petroleum ether extract exhibited significant antipyretic activity after 90 minutes (37.56±0.20) and 120 minutes (37.33± 0.14) as compared to standard group (37.38±0.18). In view of the alleged antidiabetic potential of B. monsperma plant and for the claim that their leaves and stem possesses more curative properties in general, among the different extracts of B. monsperma, significant antidiabetic activity was noticed in animal groups treated with ethanol extract of stem, it had exhibited highly significant antidiabetic activity after 3 hours of administration of extract (263.53±6.28).

Item Type: Article
Uncontrolled Keywords: Petroleum ether extract, Ethanol extract, Albino rats, Pyrexia.
Subjects: Life Sciences > MLSC Manipal
Depositing User: KMC Manipal
Date Deposited: 20 Jun 2014 10:33
Last Modified: 20 Jun 2014 10:33
URI: http://eprints.manipal.edu/id/eprint/139869

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