Smart Drug Delivery Systems as Game Changers in Therapeutics

Bhandari, Amita and Naik, Anantha Nagappa and Lewis, Shaila (2013) Smart Drug Delivery Systems as Game Changers in Therapeutics. Systematic Reviews in Pharmacy, 4 (1). pp. 1-6. ISSN 0975-8453

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Smart Drug Delivery Systems (SDDS) have emerged as panacea for many clinically useful drugs weighed down with toxicity. The discovery of Amphotericin B as a liposome has raised hopes and directed mammoth efforts in SDDS. The concept of manipulation of toxicity has given rise to additional significant approaches like targeting and use of physico-chemical approaches.Currently the spectrum of SDDS comprises of targeting liposomes, drug loaded biodegradable microspheres, stimuli responsive drug polymer conjugates, smart hydrogels, polymeric micellar particles, intelligent lipoprotein carriers, and nano carriers. There is a wealth of knowledge accumulated worldwide in the area of SDDS, which can be extremely beneficial to industry as well as practitioners of health care. In this article an overview of developments are reviewed.

Item Type: Article
Uncontrolled Keywords: Liposomes; Smart drug delivery systems; Stimuli responsive
Subjects: Pharmacy > MCOPS Manipal > Pharmaceutics
Pharmacy > MCOPS Manipal > Pharmacy Management
Depositing User: KMC Manipal
Date Deposited: 09 Jul 2014 09:26
Last Modified: 09 Jul 2014 09:26

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