A rare case of haemolytic disease of newborn with Bombay phenotype mother

Shastry, Shamee and Lewis, Leslie and Bhat, Sudha S (2013) A rare case of haemolytic disease of newborn with Bombay phenotype mother. Asian Journal of Transfusion Science, 7 (2). pp. 153-155. ISSN 0973-6247

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Abstract

We are reporting a rare case of severe hemolytic disease of newborn (HDN) with Bombay phenotype mother. A retrospective study of a case with severe haemolytic disease of newborn with Bombay phenotype mother was done. Blood grouping, antibody screening, and lectin study was done on the blood sample of the baby and mother to confirm the diagnosis. Hematological and biochemical parameters were obtained from the hospital laboratory information system for the analysis. Blood group of the baby was A positive, direct antiglobulin test was negative. Blood group of the mother was confirmed to be Bombay phenotype, Hematological parameters showed all the signs of ongoing hemolysis and the bilirubin level was in the zone of exchange transfusion. Due to the unavailability of this rare phenotype blood unit, baby was managed conservatively. Anticipating the fetal anemia and HDN with mothers having Bombay phenotype and prior notification to the transfusion services will be of great help in optimizing the neonatal care and outcome.

Item Type: Article
Uncontrolled Keywords: Blood grouping; Bombay phenotype; hemolytic disease of newborn.
Subjects: Medicine > KMC Manipal > Immunohematology and Blood Transfusion
Medicine > KMC Manipal > Paediatrics
Depositing User: KMC Manipal
Date Deposited: 19 Jul 2014 11:17
Last Modified: 17 Mar 2017 04:57
URI: http://eprints.manipal.edu/id/eprint/140184

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