Spectrum of bacteria isolated from bronchoalveolar lavage in a tertiary care centre

*, Sowmya K. N and Bhat, Sevitha and Saralaya, Vishwas (2014) Spectrum of bacteria isolated from bronchoalveolar lavage in a tertiary care centre. Journal of Evolution of Medical and Dental Sciences, 3 (28). pp. 7950-7954. ISSN 2278-4802

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Pneumonia is an inflammatory condition of the lung caused by bacteria, viruses, fungi and parasites. The common bacterial pathogens include Pseudomonas spp., Klebsiella pneumoniae, S. aureus, Acinetobacter spp., Streptococcus pneumoniae. Antibiotic resistance is common among these bacterial isolates. This study was taken up to identify the spectrum of bacteria isolated from bronchoalveolar (BAL) samples of patients suffering from lower respiratory tract infections and to determine their antibiogram. MATERIALS and METHODS: The retrospective study was carried out in a tertiary care centre over a period of one year (March 2013-February 2014).Patients above 18 years with clinical suspicion of pneumonia were included in this study. The samples with growth >104 CFU/ml of bacteria were identified and their susceptibility pattern to various antibiotics was performed. RESULTS: Out of 307 BAL samples, 110 were culture positive. The common bacterial pathogens isolated were Pseudomonas spp. (21.8%), Acinetobacter spp. (15.5%), Klebsiella spp.(14.5%), Enterococcus spp.(10.9%) and S.aureus (12.7%). Carbapenem resistance was seen in 31.6% of Acinetobacter spp, 22% Klebsiella spp. and 14% in Pseudomonas spp. Methicillin resistance was detected in 21.4% of S.aureus isolates. All strains of S.aureus were sensitive to vancomycin and teicoplanin. All isolates of Enterococci were sensitive to vancomycin, teicoplanin and high level aminoglycosides. CONCLUSION: Pseudomonas and Acinetobacter spp. were the most common bacterial pathogens isolated from BAL. Carbapenem resistance is on the rise among these gram negative bacterial isolates.

Item Type: Article
Uncontrolled Keywords: BAL, Bacteria, Antibiotic resistance.
Subjects: Medicine > KMC Mangalore > Microbiology
Depositing User: KMCMLR User
Date Deposited: 24 Jul 2014 10:41
Last Modified: 24 Jul 2014 10:41
URI: http://eprints.manipal.edu/id/eprint/140226

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