Analgesic Effect of Methanolic Extract of Vetiveria Zizanoides in Wistar Rats

Chogtu, Bharti and Nayak, Veena and Pradeep, AN (2014) Analgesic Effect of Methanolic Extract of Vetiveria Zizanoides in Wistar Rats. Journal of Drug Discovery and Therapeutics , 2 (4). pp. 1-3. ISSN 2320 - 4230

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Abstract

Introduction: Vetiveria zizanoides is used as a traditional medicine for a number of conditions, but there is lack of scientific data regarding its analgesic action. Aim: to study the analgesic action of methanolic extract of Vetiveria zizanoides (VZ) on animal models of analgesia. Methods: The animals were divided in to four groups (n=6). The groups received gum acacia, tramadol, VZ 300mg/kg and VZ 500 mg/kg orally. The analgesic effect of the plant extract was tested using hot plate and tail flick models. Results: VZ500 mg/kg produced a significant analgesic action in both the models of analgesia which was comparable to that of tramadol. VZ 300mg/kg produced significant analgesic action only hot plate model. Conclusion: The present study suggests the central analgesic action of methanolic extract of Vetiveria zizanoides. Further studies are required to confirm its analgesic action.

Item Type: Article
Uncontrolled Keywords: Vetiveria zizanoides; Methanolic extract; Analgesia
Subjects: Pharmacy > MCOPS Manipal > Pharmacology
Depositing User: KMC Manipal
Date Deposited: 05 Aug 2014 10:40
Last Modified: 05 Aug 2014 10:40
URI: http://eprints.manipal.edu/id/eprint/140337

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