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Experimental evaluation of Pentas lanceolata flowers for wound healing activity in rats

Nayak, Satheesha B and Vinutha, B and Geetha, B and Sudha, B (2005) Experimental evaluation of Pentas lanceolata flowers for wound healing activity in rats. Fitoterapia, 76 (7-8). pp. 671-675.

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Abstract

The ethanolic extract of the flowers of Pentas lanceolata given by oral route to rats at dose of 150 mg kg(-1) day(-1) for 10 days, was studied for its effect on wound healing, using excision wound mode. Significant increase in granulation tissue weight, tensile strength, hydroxyproline and glycosaminoglycan content was observed. Moderate increase in protein content was seen. There was significant reduction in the wound area measurement of the test group as compared to that of controls. The efficacious prohealing action may be due to increased collagen deposition as well as better alignment and maturation.

Item Type: Article
Uncontrolled Keywords: Pentas lanceolata; Wound healing; Excision model; Auto CAD RL 14.
Subjects: Medicine > KMC Manipal > Biochemistry
Medicine > KMC Manipal > Pathology
Depositing User: KMC Manipal
Date Deposited: 23 Aug 2014 11:22
Last Modified: 23 Aug 2014 11:22
URI: http://eprints.manipal.edu/id/eprint/140440

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