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Serum copper, ceruloplasmin and thiobarbituric acid reactive substance status in patients with ovarian cancer

Nayak, Shivananda B and Bhat, Vinutha R and Mayya, Shreemathi S (2004) Serum copper, ceruloplasmin and thiobarbituric acid reactive substance status in patients with ovarian cancer. Indian Journal of Physiology and Pharmacology, 48 (4). pp. 486-488.

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Abstract

Serum copper, ceruloplasmin and thiobarbituric acid reactive substances (TBARS) were estimated in 30 patients of ovarian cancer. The copper to ceruloplasmin ratio was moderately increased (P<0.05) but the copper (P<0.01( and ceruloplasmin (P<0.001) levels were significantly increased in ovarian cancer patients as compared to controls. TBARS levels were also found to be highly significant (P<0.001). Trace elements and free radicals have been implicated in the etiology of cancer. Hence the estimation of antioxidants like ceruloplasmin and TBARS along with the trace element like copper may be of value in the early diagnosis of cancer.

Item Type: Article
Uncontrolled Keywords: ovarian cancer; copper; thiobarbituric acid reactive ceruloplasmin; substance.
Subjects: Medicine > KMC Manipal > Biochemistry
Depositing User: KMC Manipal
Date Deposited: 25 Aug 2014 06:54
Last Modified: 05 Nov 2016 09:41
URI: http://eprints.manipal.edu/id/eprint/140447

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