Rectal Misoprostol versus Vaginal Misoprostol for first Trimester terminationof Pregnancy

Arora, Garima and *, Anupama Suresh Y and *, Shameem V. P. A and *, Suresh Y. V (2014) Rectal Misoprostol versus Vaginal Misoprostol for first Trimester terminationof Pregnancy. Journal of Evolution of Medical and Dental Sciences, 3 (14). pp. 5021-5029. ISSN 2278-4802

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Abstract

There arevarious methods have been described for preoperative cervical priming prior to vacuum aspiration (VA) in first trimester pregnancy termination, to facilitate cervical dilatation and shorten the abortion procedure. Recently, misoprostol has been globally the most investigated drug for medical abortion. Misoprostol is affordable, is easily stored at room temperature, and possesses a shelf life of several years. In our prospective interventional comparative studymisoprostol(800 μg) administered per vaginally was compared to misoprostol(800 μg) administered per rectally for first trimester termination of pregnancy and were observed for spontaneous expulsion of products of conception. The complete abortion rate was 62.86% in vaginal group in contrast to 20% in rectal group which was statically significant and majority of cases in rectal group had incomplete abortions. In vaginal group, patients with < 8 weeks gestational age aborted completely comparable to the patients with gestational age 8-12 weekswhile in rectal group, patients< 8 weeks gestational age had aborted completely in contrast to the patients with gestational age 8-12 weeks which was significant statistically and hence the efficacy of rectal misoprostol was found better at lower gestational ages (<8 weeks).

Item Type: Article
Uncontrolled Keywords: Mesoprostol pregnancy medical termination.
Subjects: Medicine > KMC Mangalore > Anaesthesiology
Medicine > KMC Mangalore > Obstetrics & Gynaecology
Depositing User: KMCMLR User
Date Deposited: 30 Aug 2014 06:52
Last Modified: 30 Aug 2014 06:52
URI: http://eprints.manipal.edu/id/eprint/140496

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