Khan, Shamim Amanulla and *, Shyam Sudhir and Mubeen, Faheem (2014) Serum Creatinine monitoring in birth asphyxiated newborns. Karnataka Paediatric Journal, 29 (1). pp. 31-35.

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Abstract

Objective: To understand the need for monitoring creatinine levels in Birth asphyxiated neonates to evaluate the possibility of Acute Kidney Injury in them. Study Design: prospective hospital based observational study done in Department of Pediatrics, Yenepoya Medical College, and Mangalore, India between Jan 2013 � June 2013. Patients: 25 newborns born with an Apgar score (A/S) of =5 at 5 min and admitted in the NICU were studied, renal function parameters�blood urea, serum creatinine, serum electrolytes were monitored initially within 24 hours of birth and then serially everyday up to day 5 of life. Results: The newborns were divided in two groups. Asphyxiated babies with normal renal functions were selected as group A and with impaired renal functions, as Group B. The renal function parameters of group A did not show any significant variation in the serial estimation, which though was elevated on Day 1 of life became normalised by Day 3, whereas in group B, renal function parameters exhibited progressively higher levels in the serial estimation of the values from day 1 to day 5. Conclusion: Monitoring of serum creatinine is recommended in asphyxiated neonates with altered renal parameters on day 1 of life to evaluate the possibility of acute kidney injury in them.

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